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Antibodies

AEN Antibody

Product Sizes
50 ug
£186.00
CSB-PA819883LA01HU-50UG
100 ug
£334.00
CSB-PA819883LA01HU-100UG
About this Product
SKU:
CSB-PA819883LA01HU
Additional Names:
Aen antibody; AEN_HUMAN antibody; apoptosis enhancing nuclease antibody; Apoptosis-enhancing nuclease antibody; Interferon stimulated exonuclease gene 20kDa like 1 antibody; Interferon stimulated exonuclease gene 20kDa like 1; isoform CRA_a antibody; Interferon-stimulated 20 kDa exonuclease-like 1 antibody; ISG20L1 antibody; pp12744 antibody
Application:
ELISA, Immunofluorescence
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
Host:
Rabbit
Immunogen:
Recombinant Human Apoptosis-enhancing nuclease protein (117-325AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
Immunofluorescence staining of HepG2 cells with CSB-PA819883LA01HU at 1:530, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).