APOBEC3F Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA816878LB01HU-50UG
100 ug
£334.00
CSB-PA816878LB01HU-100UG
About this Product
- SKU:
- CSB-PA816878LB01HU
- Additional Names:
- A3F antibody; ABC3F_HUMAN antibody; APOBEC3F antibody; Apolipoprotein B mRNA editing enzyme; catalytic polypeptide like 3F antibody; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F antibody; ARP8 antibody; DNA dC->dU-editing enzyme APOBEC-3F antibody; Induced upon T cell activation antibody; KA6 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA dC->dU-editing enzyme APOBEC-3F protein (139-287AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:APOBEC3F-Antibody-HRP-conjugated-12781401.html
