IFNL3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA810313ESR1HU-50UL
100 ul
£334.00
CSB-PA810313ESR1HU-100UL
About this Product
- SKU:
- CSB-PA810313ESR1HU
- Additional Names:
- Cytokine ZCYTO22 antibody; IFN-lambda-3 antibody; IFN-lambda-4 antibody; IL-28B antibody; IL-28C antibody; IL28B antibody; IL28B_HUMAN antibody; IL28C antibody; Interferon lambda-3 antibody; Interferon lambda-4 antibody; interleukin 28B (interferon; lambda 3) antibody; Interleukin 28C antibody; Interleukin-28B antibody; Interleukin-28C antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interferon lambda-3 protein (22-196AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IFNL3-Antibody-11089696.html
