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Antibodies

HIPK1 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA803159LC01HU-50UG
100 ug
£334.00
CSB-PA803159LC01HU-100UG
About this Product
SKU:
CSB-PA803159LC01HU
Additional Names:
Hipk 1 antibody; Hipk1 antibody; HIPK1_HUMAN antibody; Homeodomain interacting protein kinase 1 antibody; Homeodomain interacting protein kinase 1 like protein antibody; Homeodomain-interacting protein kinase 1 antibody; Myak antibody; Nbak 2 antibody; Nbak2 antibody; Nuclear body associated kinase 2 antibody; Nuclear body associated kinase 2b antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.
Host:
Rabbit
Immunogen:
Recombinant Human Homeodomain-interacting protein kinase 1 protein (1007-1151AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody