LAYN Antibody
Product Sizes
50 ul
£186.00
CSB-PA797998-50UL
100 ul
£334.00
CSB-PA797998-100UL
About this Product
- SKU:
- CSB-PA797998
- Additional Names:
- Layilin antibody; LAYN antibody; LAYN_HUMAN antibody; UNQ208/PRO234 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Layilin is a recently cloned ~55-kDa membrane-binding partner for talin (Borowsky and Hynes, 1998 ) that is widely expressed in different cell types and tissue extracts. It is found in peripheral ruffles of spreading cells and is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments. Layilin colocalizes with talin in ruffles and binds to talin's ~50-kDa head domain (amino acids 280-435). Other parts of talin (the ~220-kDa tail fragment) can bind B Beta-integrin cytoplasmic tails, vinculin, and F-actin and hence form an integrin-cytoskeleton linkage at sites of cell-substratum contact. Layilin's extracellular domain is homologous with the carbohydrate-recognition domains (CRD) of C-type lectins.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human LAYN
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:LAYN-Antibody-11103199.html
