NR3C1 (Ab-211) Antibody
Product Sizes
100 ul
£332.00
CSB-PA784840-100UL
About this Product
- SKU:
- CSB-PA784840
- Additional Names:
- GCCR antibody; GCR antibody; GCR_HUMAN antibody; GCRST antibody; glucocorticoid nuclear receptor variant 1 antibody; Glucocorticoid receptor antibody; GR antibody; GRL antibody; Grl1 antibody; nr3c1 antibody; Nuclear receptor subfamily 3 group C member 1 antibody; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. Zhen Wang, Mol. Endocrinol., Mar 2007; 21: 625 - 634. Aaron L. Miller, Mol. Endocrinol., Jun 2005; 19: 1569 - 1583. Paul J. LeBlanc, J. Physiol., Jun 2004; 557: 559 - 570. JosXavier-Neto, Hypertension, Jul 1999; 34: 31.
- Host:
- Rabbit
- Immunogen:
- Synthesized non-phosphopeptide derived from Human GR around the phosphorylation site of serine 211 (N-E-S-P-W).
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NR3C1-Ab-211-Antibody-11084305.html
