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Antibodies

DUSP12 Antibody

Product Sizes
50 ul
£186.00
CSB-PA774733-50UL
100 ul
£334.00
CSB-PA774733-100UL
About this Product
SKU:
CSB-PA774733
Additional Names:
Dual specificity phosphatase 12 antibody; Dual specificity protein phosphatase 12 antibody; Dual specificity tyrosine phosphatase YVH1 antibody; DUS12_HUMAN antibody; DUSP 1 antibody; DUSP 12 antibody; DUSP1 antibody; DUSP12 antibody; Serine/threonine specific protein phosphatase antibody; TDSP4 antibody; YVH 1 antibody; YVH1 antibody; YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog antibody; YVH1 protein tyrosine phosphatase ortholog antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Host:
Rabbit
Immunogen:
Fusion protein of Human DUSP12
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody