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Antibodies

TAOK1 Antibody, Biotin conjugated

Product Sizes
50 ul
£186.00
CSB-PA752101LD01HU-50UL
100 ul
£334.00
CSB-PA752101LD01HU-100UL
About this Product
SKU:
CSB-PA752101LD01HU
Additional Names:
2810468K05Rik antibody; AU020252 antibody; D130018F14Rik antibody; EC 2.7.11.1 antibody; FLJ14314 antibody; hKFC B antibody; hKFC-B antibody; KIAA1361 antibody; Kinase from chicken homolog B antibody; MAP3K16 antibody; MARK kinase antibody; MARKK antibody; MGC29021 antibody; Microtubule affinity regulating kinase kinase antibody; mKIAA1361 antibody; Prostate-derived sterile 20-like kinase 2 antibody; PSK2 antibody; Serine/threonine kinase TAO1 antibody; Serine/threonine protein kinase TAO1 antibody; Serine/threonine protein kinase TAO1 homolog antibody; Serine/threonine-protein kinase TAO1 antibody; STE20 like kinase antibody; STE20 like kinase PSK2 antibody; STE20-like kinase PSK2 antibody; TAO kinase 1 antibody; Taok1 antibody; TAOK1_HUMAN antibody; Thousand and one amino acid protein 1 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.
Host:
Rabbit
Immunogen:
Recombinant Human Serine/threonine-protein kinase TAO1 protein (400-659AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody