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Antibodies

SIGIRR Antibody

Product Sizes
50 ul
£186.00
CSB-PA743558ESR1HU-50UL
100 ul
£334.00
CSB-PA743558ESR1HU-100UL
About this Product
SKU:
CSB-PA743558ESR1HU
Additional Names:
Ig IL1 related receptor antibody; MGC110992 antibody; SIGIR_HUMAN antibody; SIGIRR antibody; Single Ig IL 1 related receptor antibody; Single Ig IL-1-related receptor antibody; Single Ig IL-1R-related molecule antibody; Single Ig IL1R Related Molecule antibody; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody; Single immunoglobulin and toll interleukin 1 receptor domain antibody; Single immunoglobulin domain containing IL1R related protein antibody; Single immunoglobulin domain IL1R1 related antibody; Single immunoglobulin domain-containing IL1R-related protein antibody; TIR 8 antibody; TIR8 antibody; Toll/interleukin 1 receptor 8 antibody; Toll/interleukin-1 receptor 8 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Host:
Rabbit
Immunogen:
Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody