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Antibodies

EID3 Antibody

Product Sizes
50 ul
£186.00
CSB-PA731077-50UL
100 ul
£334.00
CSB-PA731077-100UL
About this Product
SKU:
CSB-PA731077
Additional Names:
E1A-like inhibitor of differentiation 3 antibody; EID 3 antibody; EID-1-like inhibitor of differentiation 3 antibody; EID-3 antibody; EID3 antibody; EID3_HUMAN antibody; EP300 interacting inhibitor of differentiation 3 antibody; EP300-interacting inhibitor of differentiation 3 antibody; FLJ25832 antibody; Non-SMC element 4; S. cerevisiae; homolog of; B antibody; Non-structural maintenance of chromosomes element 4 homolog B antibody; NSE4B antibody; NSMCE4B antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human EID3
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody