KHDRBS2 Antibody
Product Sizes
50 ug
£186.00
CSB-PA730139LA01HU-50UG
100 ug
£334.00
CSB-PA730139LA01HU-100UG
About this Product
- SKU:
- CSB-PA730139LA01HU
- Additional Names:
- KH domain containing; RNA binding; signal transduction associated protein 2 antibody; 6330586C16Rik antibody; bA535F17.1 antibody; FLJ38664 antibody; hSLM 1 antibody; hSLM-1 antibody; KH domain containing; RNA binding; signal transduction associated 2 antibody; KH domain-containing antibody; KHDR2_HUMAN antibody; khdrbs2 antibody; MGC26664 antibody; RNA-binding antibody; Sam68 like mammalian protein 1 antibody; Sam68-like mammalian protein 1 antibody; signal transduction-associated protein 2 antibody; SLM 1 antibody; SLM-1 antibody; SLM1 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:KHDRBS2-Antibody-11114021.html
