Phospho-SP1 (Thr739) Antibody
Product Sizes
100 ul
£402.00
CSB-PA730012-100UL
About this Product
- SKU:
- CSB-PA730012
- Additional Names:
- SP 1 antibody; SP1 antibody; Sp1 transcription factor antibody; SP1_HUMAN antibody; Specificity protein 1 antibody; Transcription factor Sp1 antibody; TSFP 1 antibody; TSFP1 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-a G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. Thiesen HJ,et al.(1990)Nucleic Acids Res.18(11):3203-9. Zutter MM,et al.(1997) Blood.90(2):678-89. Lou Z,et al.(2005)Cancer Res.65(3):1007-17
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 739 (T-A-T(p)-P-S) derived from Human SP1
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:Phospho-SP1-Thr739-Antibody-11083236.html
