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Antibodies

Genome polyprotein Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA714772LD01HYH-50UG
100 ug
£334.00
CSB-PA714772LD01HYH-100UG
About this Product
SKU:
CSB-PA714772LD01HYH
Additional Names:
antibody; Genome polyprotein [Cleaved into: P1; Capsid protein VP0 antibody; VP4-VP2); Capsid protein VP4 antibody; P1A antibody; Virion protein 4); Capsid protein VP2 antibody; P1B antibody; Virion protein 2); Capsid protein VP3 antibody; P1C antibody; Virion protein 3); Capsid protein VP1 antibody; P1D antibody; Virion protein 1); P2; Protease 2A antibody; P2A antibody; EC 3.4.22.29 antibody; Picornain 2A antibody; Protein 2A); Protein 2B antibody; P2B); Protein 2C antibody; P2C antibody; EC 3.6.1.15); P3; Protein 3AB; Protein 3A antibody; P3A); Viral protein genome-linked antibody; VPg antibody; Protein 3B antibody; P3B); Protein 3CD antibody; EC 3.4.22.28); Protease 3C antibody; EC 3.4.22.28 antibody; Picornain 3C antibody; P3C); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48 antibody; 3D polymerase antibody; 3Dpol antibody; Protein 3D antibody; 3D)] antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Capsid protein VP1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor to provide virion attachment to target host cells. This attachment induces virion internalization. Tyrosine kinases are probably involved in the entry process. After binding to its receptor, the capsid undergoes conformational changes. Capsid protein VP1 N-terminus (that contains an amphipathic alpha-helix) and capsid protein VP4 are externalized. Together, they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been released, the channel shrinks.
Host:
Rabbit
Immunogen:
Recombinant Human enterovirus 71 Genome polyprotein protein (566-862AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody