PCID2 Antibody
Product Sizes
50 ug
£186.00
CSB-PA705514LA01HU-50UG
100 ug
£334.00
CSB-PA705514LA01HU-100UG
About this Product
- SKU:
- CSB-PA705514LA01HU
- Additional Names:
- CSN12 like protein antibody; CSN12-like protein antibody; DKFZp686C20226 antibody; F10 antibody; FLJ11305 antibody; FLJ99362 antibody; HT004 antibody; MGC16774 antibody; PCI domain containing 2 antibody; PCI domain containing protein 2 antibody; PCI domain-containing protein 2 antibody; PCID2 antibody; PCID2_HUMAN antibody; RP11 - 98F14.6 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PCI domain-containing protein 2 protein (2-250AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PCID2-Antibody-12554410.html
