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Antibodies

KLHL12 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA700650LC01HU-50UG
100 ug
£334.00
CSB-PA700650LC01HU-100UG
About this Product
SKU:
CSB-PA700650LC01HU
Additional Names:
C3IP1 antibody; CUL3 interacting protein 1 antibody; CUL3-interacting protein 1 antibody; DKIR antibody; DKIR homolog antibody; FLJ27152 antibody; hDKIR antibody; Kelch like 12 (Drosophila) antibody; Kelch like 12 antibody; Kelch like 12 variant antibody; Kelch like protein 12 antibody; Kelch like protein C3IP1 antibody; kelch-like family member 12 antibody; Kelch-like protein 12 antibody; KLH12_HUMAN antibody; KLHL 12 antibody; klhl12 antibody; OTTHUMP00000038799 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
Host:
Rabbit
Immunogen:
Recombinant Human Kelch-like protein 12 protein (1-220AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody