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Antibodies

HIF1AN Antibody

Product Sizes
50 ul
£186.00
CSB-PA699624-50UL
100 ul
£334.00
CSB-PA699624-100UL
About this Product
SKU:
CSB-PA699624
Additional Names:
DKFZp762F1811 antibody; Factor inhibiting HIF-1 antibody; Factor inhibiting HIF1 antibody; FIH 1 antibody; FIH-1 antibody; FIH1 antibody; FLJ20615 antibody; FLJ22027 antibody; HIF1AN antibody; HIF1N_HUMAN antibody; Hypoxia inducible factor 1 alpha inhibitor antibody; Hypoxia inducible factor 1 alpha subunit inhibitor antibody; Hypoxia inducible factor asparagine hydroxylase antibody; Hypoxia-inducible factor 1-alpha inhibitor antibody; Hypoxia-inducible factor asparagine hydroxylase antibody; Peptide aspartate beta dioxygenase antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene. Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins
Host:
Rabbit
Immunogen:
Synthetic peptide of Human HIF1AN
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody