TYROBP Antibody
Product Sizes
50 ul
£186.00
CSB-PA699424-50UL
100 ul
£334.00
CSB-PA699424-100UL
About this Product
- SKU:
- CSB-PA699424
- Additional Names:
- DAP 12 antibody; DAP12 antibody; DNAX activation protein 12 antibody; DNAX-activation protein 12 antibody; KAR-associated protein antibody; KARAP antibody; Killer activating receptor associated protein antibody; Killer-activating receptor-associated protein antibody; PLOSL antibody; TYOBP_HUMAN antibody; TYRO protein tyrosine kinase binding protein antibody; TYRO protein tyrosine kinase-binding protein antibody; TYROBP antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human TYROBP
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TYROBP-Antibody-11102838.html
