DKK3 Antibody
Product Sizes
100 ul
£332.00
CSB-PA694792-100UL
About this Product
- SKU:
- CSB-PA694792
- Additional Names:
- Dickkopf 3 antibody; Dickkopf 3 homolog (Xenopus laevis) antibody; Dickkopf 3 homolog antibody; Dickkopf homolog 3 antibody; Dickkopf related protein 3 antibody; Dickkopf related protein 3 Precursor antibody; Dickkopf WNT signaling pathway inhibitor 3 antibody; Dickkopf; Xenopus; homolog of; 3 antibody; Dickkopf-3 antibody; Dickkopf-related protein 3 antibody; Dickkopf3 antibody; DKK 3 antibody; Dkk-3 antibody; DKK3 antibody; DKK3_HUMAN antibody; hDkk 3 antibody; hDkk-3 antibody; hDkk3 antibody; Regulated in glioma antibody; REIC antibody; RIG antibody; RIG-like 5-6 antibody; RIG-like 7-1 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease By similarity. Shimizu K., Gene 282:151-158(2002). Gray A.M., Genome Res. 13:2265-2270(2003). Niehrs C., Oncogene 25:7469-7481(2006).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human DKK3.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DKK3-Antibody-11085845.html
