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Antibodies

MBD3 Antibody

Product Sizes
100 ul
£332.00
CSB-PA693569-100UL
About this Product
SKU:
CSB-PA693569
Additional Names:
AI181826 antibody; AU019209 antibody; MBD 3 antibody; Mbd3 antibody; MBD3: methyl CpG binding domain protein 3 antibody; MBD3_HUMAN antibody; Methyl CpG binding domain protein 3 antibody; Methyl CpG binding protein MBD3 antibody; Methyl-CpG-binding domain protein 3 antibody; Methyl-CpG-binding protein MBD3 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases. Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998). Grimwood J., Nature 428:529-535(2004). Tatematsu K., Genes Cells 5:677-688(2000).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from C-terminal of Human MBD3.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody