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Antibodies

DUSP6 Antibody

Product Sizes
50 ul
£186.00
CSB-PA625538-50UL
100 ul
£334.00
CSB-PA625538-100UL
About this Product
SKU:
CSB-PA625538
Additional Names:
Dual specificity phosphatase 6 antibody; Dual specificity phosphatase 6 isoform a antibody; Dual specificity protein phosphatase 6 antibody; Dual specificity protein phosphatase PYST1 antibody; DUS6_HUMAN antibody; DUSP 6 antibody; DUSP 6a antibody; Dusp6 antibody; DUSP6a antibody; HH19 antibody; MAP kinase phosphatase 3 antibody; Mitogen activated protein kinase phosphatase 3 antibody; Mitogen-activated protein kinase phosphatase 3 antibody; MKP 3 antibody; MKP-3 antibody; MKP3 antibody; PYST 1 antibody; PYST1 antibody; Serine/threonine specific protein phosphatase antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Fusion protein of Human DUSP6
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody