ACKR1 Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA624105LC01HU-50UG
100 ug
£334.00
CSB-PA624105LC01HU-100UG
About this Product
- SKU:
- CSB-PA624105LC01HU
- Additional Names:
- ACKR1 antibody; Atypical chemokine receptor 1 antibody; CCBP1 antibody; CD234 antibody; DARC antibody; Dfy antibody; Duffy antigen/chemokine receptor antibody; duffy blood group antibody; Duffy blood group antigen antibody; Duffy blood group chemokine receptor antibody; DUFFY_HUMAN antibody; FY antibody; Fy glycoprotein antibody; Glycoprotein D antibody; GPD antibody; GpFy antibody; Plasmodium vivax receptor antibody; WBCQ1 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Atypical chemokine receptor 1 protein (1-63AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ACKR1-AntibodyFITC-conjugated-11098242.html
