SART3 Antibody
Product Sizes
50 ug
£186.00
CSB-PA624010HA01HU-50UG
100 ug
£334.00
CSB-PA624010HA01HU-100UG
About this Product
- SKU:
- CSB-PA624010HA01HU
- Additional Names:
- DSAP1 antibody; hSART 3 antibody; hSART-3 antibody; P100 antibody; P110 antibody; p110(nrb) antibody; RP11 13G14 antibody; SART 3 antibody; SART-3 antibody; SART3 antibody; SART3_HUMAN antibody; Squamous cell carcinoma antigen recognized by T cells 3 antibody; Squamous cell carcinoma antigen recognized by T-cells 3 antibody; Tat interacting protein of 110 kDa antibody; Tat-interacting protein of 110 kDa antibody; Tip110 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:SART3-Antibody-11108805.html
