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Antibodies

KCNMB1 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA621958LC01HU-50UG
100 ug
£334.00
CSB-PA621958LC01HU-100UG
About this Product
SKU:
CSB-PA621958LC01HU
Additional Names:
BK channel beta subunit antibody; BK channel subunit beta 1 antibody; BK channel subunit beta-1 antibody; BKbeta antibody; BKbeta1 antibody; Calcium activated potassium channel subfamily M subunit beta 1 antibody; Calcium activated potassium channel subunit beta 1 antibody; Calcium activated potassium channel subunit beta antibody; Calcium-activated potassium channel antibody; Calcium-activated potassium channel subunit beta antibody; Calcium-activated potassium channel subunit beta-1 antibody; Charybdotoxin receptor subunit beta 1 antibody; Charybdotoxin receptor subunit beta-1 antibody; Hbeta1 antibody; hslo beta antibody; K(VCA)beta 1 antibody; K(VCA)beta antibody; K(VCA)beta-1 antibody; KCMB1_HUMAN antibody; KCNMB 1 antibody; Kcnmb1 antibody; Large conductance Ca2+ activated K+ channel beta 1 subunit antibody; Maxi K channel beta subunit antibody; Maxi K channel subunit beta 1 antibody; Maxi K channel subunit beta-1 antibody; Potassium large conductance calcium activated channel subfamily M beta member 1 antibody; Slo beta 1 antibody; SLO beta antibody; Slo-beta antibody; Slo-beta-1 antibody; subfamily M subunit beta-1 antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
Host:
Rabbit
Immunogen:
Recombinant Human Calcium-activated potassium channel subunit beta-1 protein (40-130AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody