TNIP1 Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA619959LB01HU-50UG
100 ug
£334.00
CSB-PA619959LB01HU-100UG
About this Product
- SKU:
- CSB-PA619959LB01HU
- Additional Names:
- ABIN 1 antibody; HIV-1 Nef-interacting protein antibody; hVAN antibody; KIAA0113 antibody; Naf1 antibody; Nef-associated factor 1 antibody; Nip40-1 antibody; TNFAIP3 interacting protein 1 antibody; TNFAIP3-interacting protein 1 antibody; TNIP-1 antibody; Tnip1 antibody; TNIP1_HUMAN antibody; VAN antibody; Virion-associated nuclear shuttling protein antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human TNFAIP3-interacting protein 1 protein (526-636AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TNIP1-Antibody-HRP-conjugated-12783529.html
