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Antibodies

GRIK2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA618751LA01HU-50UL
100 ul
£334.00
CSB-PA618751LA01HU-100UL
About this Product
SKU:
CSB-PA618751LA01HU
Additional Names:
bA487F5.1 antibody; EAA4 antibody; Excitatory amino acid receptor 4 antibody; GLR 6 antibody; GLR6 antibody; GluK2 antibody; GLUK6 antibody; GLUR 6 antibody; GluR-6 antibody; GluR6 antibody; Glutamate receptor 6 antibody; Glutamate receptor antibody; glutamate receptor form A antibody; glutamate receptor form B antibody; glutamate receptor form C antibody; glutamate receptor form D antibody; glutamate receptor form E antibody; Glutamate receptor ionotropic kainate 2 antibody; GRIK 2 antibody; GRIK2 antibody; GRIK2 protein antibody; GRIK2_HUMAN antibody; ionotropic kainate 2 antibody; MRT6 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:28180184). May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Glutamate receptor ionotropic, kainate 2 protein (203-500AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
Immunofluorescence staining of SH-SY5Y cells with CSB-PA618751LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA618751LA01HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.