BNIP3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA618642ESR1HU-50UL
100 ul
£334.00
CSB-PA618642ESR1HU-100UL
About this Product
- SKU:
- CSB-PA618642ESR1HU
- Additional Names:
- BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibody; BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody; BNIP 3 antibody; BNIP3 antibody; BNIP3_HUMAN antibody; NIP 3 antibody; NIP3 antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:BNIP3-Antibody-1091071.html
