KCNMA1 Antibody, Biotin conjugated
Product Sizes
50 ug
£186.00
CSB-PA614255LD01HU-50UG
100 ug
£334.00
CSB-PA614255LD01HU-100UG
About this Product
- SKU:
- CSB-PA614255LD01HU
- Additional Names:
- subfamily M subunit alpha-1 antibody; BK channel antibody; BKCA alpha antibody; BKCA alpha subunit antibody; BKTM antibody; Calcium-activated potassium channel antibody; Calcium-activated potassium channel subunit alpha-1 antibody; Drosophila slowpoke like antibody; hSlo antibody; K(VCA)alpha antibody; KCa1.1 antibody; KCMA1_HUMAN antibody; KCNMA antibody; KCNMA1 antibody; Maxi K channel antibody; Maxi Potassium channel alpha antibody; MaxiK antibody; SAKCA antibody; SLO alpha antibody; SLO antibody; Slo homolog antibody; Slo-alpha antibody; Slo1 antibody; Slowpoke homolog antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Calcium-activated potassium channel subunit alpha-1 protein (1-86AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:KCNMA1-AntibodyBiotin-conjugated-11113400.html
