NAE1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA613411ESR1HU-50UL
100 ul
£334.00
CSB-PA613411ESR1HU-100UL
About this Product
- SKU:
- CSB-PA613411ESR1HU
- Additional Names:
- 59 kDa antibody; A 116A10.1 antibody; Amyloid beta precursor protein binding protein 1 59kD antibody; Amyloid beta precursor protein binding protein 1 59kDa antibody; Amyloid beta precursor protein binding protein 1 antibody; Amyloid beta precursor protein binding protein 1, 59 kDa antibody; Amyloid beta precursor protein-binding protein 1 antibody; Amyloid protein binding protein 1 antibody; Amyloid protein-binding protein 1 antibody; APP BP1 antibody; APP-BP1 antibody; APPBP 1 antibody; APPBP1 antibody; HPP 1 antibody; HPP1 antibody; NAE 1 antibody; NAE1 antibody; NEDD8 activating enzyme E1 regulatory subunit antibody; NEDD8 activating enzyme E1 subunit 1 antibody; NEDD8 activating enzyme E1 subunit antibody; NEDD8-activating enzyme E1 regulatory subunit antibody; Proto oncogene protein 1 antibody; Proto-oncogene protein 1 antibody; Protooncogene protein 1 antibody; ula 1 antibody; ULA1_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human NEDD8-activating enzyme E1 regulatory subunit protein (1-220AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NAE1-Antibody-11909781.html
