PTPRJ Antibody
Product Sizes
50 ul
£186.00
CSB-PA613274ESR1HU-50UL
100 ul
£334.00
CSB-PA613274ESR1HU-100UL
About this Product
- SKU:
- CSB-PA613274ESR1HU
- Additional Names:
- CD 148 antibody; CD148 antibody; CD148 antigen antibody; Density enhanced phosphatase 1 antibody; Density-enhanced phosphatase 1 antibody; DEP 1 antibody; DEP-1 antibody; HPTP eta antibody; HPTPeta antibody; Human density enhanced phosphatase 1 antibody; Protein tyrosine phosphatase eta antibody; Protein tyrosine phosphatase receptor type J antibody; Protein tyrosine phosphatase receptor type J polypeptide antibody; Protein-tyrosine phosphatase eta antibody; Protein-tyrosine phosphatase receptor type J antibody; PTPJ antibody; Ptprj antibody; PTPRJ_HUMAN antibody; R PTP Eta antibody; R-PTP-eta antibody; R-PTP-J antibody; Receptor type tyrosine protein phosphatase eta antibody; Receptor-type tyrosine-protein phosphatase eta antibody; SCC 1 antibody; SCC1 antibody; susceptibility to colon cancer 1; mouse; homolog of antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Receptor-type tyrosine-protein phosphatase eta protein (140-370AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PTPRJ-Antibody-11909955.html
