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Antibodies

NS Antibody

Product Sizes
50 ul
£186.00
CSB-PA604972LA01IER-50UL
100 ul
£334.00
CSB-PA604972LA01IER-100UL
About this Product
SKU:
CSB-PA604972LA01IER
Additional Names:
NS antibody; Non-structural protein 1 antibody; NS1 antibody; NS1A antibody
Application:
ELISA, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.
Host:
Rabbit
Immunogen:
Recombinant Influenza A virus Non-structural protein 1 protein (1-237AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody