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Antibodies

ALS2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA598875-50UL
100 ul
£334.00
CSB-PA598875-100UL
About this Product
SKU:
CSB-PA598875
Additional Names:
ALS 2 antibody; ALS2 antibody; ALS2_HUMAN antibody; ALS2CR6 antibody; Alsin antibody; ALSJ antibody; Amyotrophic lateral sclerosis 2 (juvenile) antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 6 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein antibody; Amyotrophic lateral sclerosis 2 protein antibody; Amyotrophic lateral sclerosis protein 2 antibody; FLJ31851 antibody; IAHSP antibody; KIAA1563 antibody; MGC87187 antibody; PLSJ antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Fusion protein of Human ALS2
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody