BCAS2 Antibody
Product Sizes
50 ul
£186.00
CSB-PA594692-50UL
100 ul
£334.00
CSB-PA594692-100UL
About this Product
- SKU:
- CSB-PA594692
- Additional Names:
- bcas2 antibody; Breast carcinoma amplified sequence 2 antibody; Breast carcinoma-amplified sequence 2 antibody; DAM 1 antibody; DAM-1 antibody; DAM1 antibody; DNA amplified in mammary carcinoma 1 protein antibody; MGC7712 antibody; Pre mRNA splicing factor SPF27 antibody; Pre-mRNA-splicing factor spf27 antibody; Snt309 antibody; SPF27 antibody; SPF27_HUMAN antibody; Spliceosome associated protein amplified in breast cancer antibody; Spliceosome associated protein SPF 27 antibody; Spliceosome-associated protein SPF 27 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TR (thyroid hormone receptor beta), ER (estrogen receptor alpha), ER, PR (progesterone receptor), and PPAR (Peroxisome proliferator-activated receptor gamma). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human BCAS2
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:BCAS2-Antibody-11100900.html
