NFKBIA (Ab-32/36) Antibody
Product Sizes
100 ul
£332.00
CSB-PA587028-100UL
About this Product
- SKU:
- CSB-PA587028
- Additional Names:
- I kappa B alpha antibody; I-kappa-B-alpha antibody; IkappaBalpha antibody; IkB-alpha antibody; IKBA antibody; IKBA_HUMAN antibody; IKBalpha antibody; MAD 3 antibody; MAD3 antibody; Major histocompatibility complex enhancer-binding protein MAD3 antibody; NF kappa B inhibitor alpha antibody; NF-kappa-B inhibitor alpha antibody; NFKBI antibody; NFKBIA antibody; Nuclear factor of kappa light chain gene enhancer in B cells antibody; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. Mattioli I, et al. (2004)J Immunol; 172(10): 6336-44. Courtois G, et al. (2003)J Clin Invest; 112(7): 1108-15. Nair A, et al. (2003) Oncogene; 22(1): 50-8. Fan C, et al. (2002)J Cell Sci; 115(Pt 24): 4843-53. Schubert SY, et al. (2002)FASEB J; 16(14): 193
- Host:
- Rabbit
- Immunogen:
- Synthesized non-phosphopeptide derived from Human IK KappaB-A Alpha around the phosphorylation site of Serine 32/36.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NFKBIA-Ab-3236-Antibody-11084373.html
