PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody
Product Sizes
100 ul
£332.00
CSB-PA583804-100UL
About this Product
- SKU:
- CSB-PA583804
- Additional Names:
- ADRB2 antibody; Alpha PAK antibody; Alpha-PAK antibody; MGC130000 antibody; MGC130001 antibody; p21 activated kinase 1 antibody; p21 protein (Cdc42/Rac) activated kinase 1 antibody; p21-activated kinase 1 antibody; p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) antibody; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) antibody; p65 PAK antibody; p65-PAK antibody; P68-PAK antibody; PAK alpha antibody; PAK-1 antibody; Pak1 antibody; PAK1_HUMAN antibody; Paka antibody; PAKalpha antibody; Protein kinase MUK2 antibody; Rac/p21-activated kinase antibody; Serine/threonine-protein kinase PAK 1 antibody; STE20 homolog yeast antibody
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. Parsons M, et al. (2005) Mol Cell Biol ; 25:1680-1695. Jung JH, et al. (2005) J Biol Chem; 280:40025-40031. Lampugnani MG, et al. (2002) Mol Biol Cell ; 13: 1175-1189 Wang RA, et al. (2002) EMBO J; 21: 5437 - 5447.
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.421~425/400~404/419~423 (R-S-T-M-V) derived from Human PAK1/PAK2/PAK3.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PAK1PAK2PAK3-Ab-423402421-Antibody-11083026.html
