MLF1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA583476-100UL
About this Product
- SKU:
- CSB-PA583476
- Additional Names:
- Hls7 antibody; MLF1 antibody; MLF1_HUMAN antibody; Myelodysplasia myeloid leukemia factor 1 antibody; Myelodysplasia-myeloid leukemia factor 1 antibody; Myeloid leukemia factor 1 antibody; myeloid leukemia factor 1 variant 1 antibody; myeloid leukemia factor 1 variant 2 antibody; myeloid leukemia factor 1 variant 3 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204]. Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101]. Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human MLF1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MLF1-Antibody-11086021.html
