MNAT1 Antibody
Product Sizes
100 ul
£332.00
CSB-PA583349-100UL
About this Product
- SKU:
- CSB-PA583349
- Additional Names:
- MNAT 1 antibody; CAP35 antibody; CDK activating kinase assembly factor MAT1 antibody; CDK-activating kinase assembly factor MAT1 antibody; CDK7/cyclin H assembly factor antibody; CDK7/cyclin-H assembly factor antibody; Cyclin G1 interacting protein antibody; Cyclin-G1-interacting protein antibody; MAT1 antibody; MAT1_HUMAN antibody; Menage a trois 1 (CAK assembly factor) antibody; Menage a trois antibody; Menage a trois homolog 1; cyclin H assembly factor (Xenopus laevis) antibody; MNAT CDK activating kinase assembly factor 1 antibody; Mnat1 antibody; p35 antibody; p36 antibody; RING finger protein 66 antibody; RING finger protein MAT1 antibody; RNF66 antibody; TFB3 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Tassan J.-P., EMBO J. 14:5608-5617(1995). Yee A., Cancer Res. 55:6058-6062(1995). Tirode F., Mol. Cell 3:87-95(1999).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human MAT1.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MNAT1-Antibody-11084985.html
