DAB2 Antibody
Product Sizes
50 ul
£186.00
CSB-PA574764-50UL
100 ul
£334.00
CSB-PA574764-100UL
About this Product
- SKU:
- CSB-PA574764
- Additional Names:
- DAB2 antibody; DOC2 antibody; Disabled homolog 2 antibody; Adaptor molecule disabled-2 antibody; Differentially expressed in ovarian carcinoma 2 antibody; DOC-2 antibody; Differentially-expressed protein 2 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human DAB2
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DAB2-Antibody-11101183.html
