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Antibodies

MAGEC2 Antibody

Product Sizes
100 ul
£332.00
CSB-PA574003-100UL
About this Product
SKU:
CSB-PA574003
Additional Names:
Cancer testis antigen 10 antibody; Cancer/testis antigen 10 antibody; CT10 antibody; HCA587 antibody; Hepatocellular cancer antigen 587 antibody; Hepatocellular carcinoma associated antigen 587 antibody; Hepatocellular carcinoma-associated antigen 587 antibody; MAGC2_HUMAN antibody; MAGE C2 antigen antibody; MAGE E1 antigen antibody; MAGE family member C2 antibody; MAGE-C2 antigen antibody; MAGE-E1 antigen antibody; MAGEC2 antibody; Melanoma antigen family C 2 antibody; Melanoma antigen family C2 antibody; Melanoma antigen family E 1 cancer/testis specific antibody; Melanoma associated antigen C2 antibody; Melanoma-associated antigen C2 antibody; MGC13377 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. Gure A.O., Int. J. Cancer 85:726-732(2000) [PubMed: 10699956]. Lucas S., Int. J. Cancer 87:55-60(2000) [PubMed: 10861452]. Wang Y., J. Immunol. 169:1102-1109(2002) [PubMed: 12097419].
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human MAGEC2.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody