DLX5 Antibody
Product Sizes
100 ul
£332.00
CSB-PA571618-100UL
About this Product
- SKU:
- CSB-PA571618
- Additional Names:
- DLX5Homeobox protein DLX-5 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. Ota T., Nat. Genet. 36:40-45(2004). Hillier L.W., Nature 424:157-164(2003). Willis D.M., J. Biol. Chem. 277:37280-37291(2002).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human DLX5.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DLX5-Antibody-11085010.html
