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Antibodies

CIT Antibody

Product Sizes
100 ul
£332.00
CSB-PA565862-100UL
About this Product
SKU:
CSB-PA565862
Additional Names:
CIT antibody; CRIK antibody; KIAA0949 antibody; STK21Citron Rho-interacting kinase antibody; CRIK antibody; EC 2.7.11.1 antibody; Serine/threonine-protein kinase 21 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2. Nagase T., DNA Res. 6:63-70(1999). Scherer S.E., Nature 440:346-351(2006). Gruneberg U., J. Cell Biol. 172:363-372(2006).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human CTRO.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody