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Antibodies

STAT5A Antibody

Product Sizes
50 ul
£186.00
CSB-PA554957-50UL
100 ul
£334.00
CSB-PA554957-100UL
About this Product
SKU:
CSB-PA554957
Additional Names:
MGF antibody; Signal transducer and activator of transcription 5A antibody; Signal Transducer and Activator of Transcription 5B antibody; STA5A_HUMAN antibody; STAT 5A antibody; STAT 5B antibody; STAT5 antibody; STAT5A antibody; STAT5B antibody; Transcription factor STAT5A antibody; Transcription factor STAT5B antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Host:
Rabbit
Immunogen:
Fusion protein of Human STAT5A
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody