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Antibodies

IKBIP Antibody

Product Sizes
50 ul
£186.00
CSB-PA505319-50UL
100 ul
£334.00
CSB-PA505319-100UL
About this Product
SKU:
CSB-PA505319
Additional Names:
IKBIP antibody; IKIP antibody; Inhibitor of nuclear factor kappa-B kinase-interacting protein antibody; I kappa-B kinase-interacting protein antibody; IKBKB-interacting protein antibody; IKK-interacting protein antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
Host:
Rabbit
Immunogen:
Fusion protein of Human IKBIP
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody