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Antibodies

Phospho-KIT (Tyr721) Antibody

Product Sizes
100 ul
£402.00
CSB-PA449794-100UL
About this Product
SKU:
CSB-PA449794
Additional Names:
C Kit antibody; c-Kit antibody; c-Kit Ligand antibody; CD117 antibody; Kit antibody; Kit Ligand antibody; KIT oncogene antibody; KIT proto oncogene receptor tyrosine kinase antibody; KIT_HUMAN antibody; Mast cell growth factor receptor antibody; Mast/stem cell growth factor receptor Kit antibody; MGF antibody; p145 c-kit antibody; PBT antibody; Piebald trait protein antibody; Proto oncogene c Kit antibody; Proto oncogene tyrosine protein kinase Kit antibody; Proto-oncogene c-Kit antibody; SCF Receptor antibody; SCFR antibody; soluble KIT variant 1 antibody; Steel Factor Receptor antibody; Stem cell factor receptor antibody; tyrosine protein kinase Kit antibody; Tyrosine-protein kinase Kit antibody; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) Nocka, K. et al. (1990) EMBO J. 9, 1805-1813. Hirota, S. et al. (1998) Science 279, 577-580. Blume-Jensen, P. et al. (2000) Nat. Genet. 24, 157-162. Sattler, M. et al. (1997) J. Biol. Chem. 272, 10248-10253. Gommerman, J.L. et al. (1997) J. Biol. Chem. 272, 30519-30525.
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 721 (N-E-Y(p)-M-D) derived from Human c-Kit.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody