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Antibodies

PRKCQ (Ab-695) Antibody

Product Sizes
100 ul
£332.00
CSB-PA443202-100UL
About this Product
SKU:
CSB-PA443202
Additional Names:
KPCT_HUMAN antibody; MGC126514 antibody; MGC141919 antibody; nPKC theta antibody; nPKC-theta antibody; nPKCtheta antibody; OTTHUMP00000043364 antibody; OTTHUMP00000043365 antibody; PKC 0 antibody; PKC0 antibody; Prkcq antibody; PRKCT antibody; Protein kinase C theta antibody; Protein kinase C theta type antibody; Protein Kinase Ctheta antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Xu ZB, et al.(2004) J Biol Chem 279:50401-50409 Thebault S, et al. (2004) Mol Immunol 40: 931-942
Host:
Rabbit
Immunogen:
Peptide sequence around aa.693~697 (N-F-S-F-M) derived from Human PKCth.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody