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Antibodies

ACVRL1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA439392-100UL
About this Product
SKU:
CSB-PA439392
Additional Names:
Activin A receptor antibody; Activin A receptor type II like 1 antibody; Activin A receptor; type II like kinase 1 antibody; Activin receptor like kinase 1 antibody; Activin receptor-like kinase 1 antibody; ACVL1_HUMAN antibody; ACVRL1 antibody; ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; Osler Rendu Weber syndrome 2 antibody; Serine/threonine protein kinase receptor R3 antibody; Serine/threonine-protein kinase receptor R3 antibody; SKR3 antibody; TGF B superfamily receptor type I antibody; TGF-B superfamily receptor type I antibody; TSR-I antibody; TSR1 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. ten Dijke P., Oncogene 8:2879-2887(1993). Attisano L., Cell 75:671-680(1993). Berg J.N., Am. J. Hum. Genet. 61:60-67(1997).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human ACVL1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody