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Antibodies

PIM2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA438428-50UL
100 ul
£334.00
CSB-PA438428-100UL
About this Product
SKU:
CSB-PA438428
Additional Names:
OTTHUMP00000025825 antibody; Pim 2 oncogene antibody; Pim 2h antibody; Pim-2h antibody; PIM2 antibody; PIM2 Oncogene antibody; PIM2_HUMAN antibody; Pim2h antibody; Proto Oncogene PIM2 antibody; Proto-oncogene Pim-2 (serine threonine kinase) antibody; Serine/threonine kinase PIM2 antibody; Serine/threonine-protein kinase Pim-2 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
Host:
Rabbit
Immunogen:
Fusion protein of Human PIM2
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody