PA Antibody
Product Sizes
50 ug
£186.00
CSB-PA395880EA01ILR-50UG
100 ug
£334.00
CSB-PA395880EA01ILR-100UG
About this Product
- SKU:
- CSB-PA395880EA01ILR
- Additional Names:
- PAPolymerase acidic protein antibody; EC 3.1.-.- antibody; RNA-directed RNA polymerase subunit P2 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. In addition of its function in viral transcription, PA also plays an essential role in viral RNA synthesis and promotes the formation of the trimeric polymerase complex.
- Host:
- Rabbit
- Immunogen:
- Recombinant Influenza A virus Polymerase acidic protein (1-716AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PA-Antibody-11082423.html
