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Antibodies

ORF1 Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA327230LD01HGE-50UG
100 ug
£334.00
CSB-PA327230LD01HGE-100UG
About this Product
SKU:
CSB-PA327230LD01HGE
Additional Names:
ORF1 antibody; Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody; EC 2.1.1.- antibody; EC 2.7.7.-); Putative papain-like cysteine protease antibody; PLP antibody; EC 3.4.22.-); NTPase/helicase antibody; EC 3.6.4.-); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48)] antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody