IFNT1 Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA322795LC01BO-50UG
100 ug
£334.00
CSB-PA322795LC01BO-100UG
About this Product
- SKU:
- CSB-PA322795LC01BO
- Additional Names:
- IFNT1 antibody; Interferon tau-1 antibody; IFN-tau-1 antibody; Antiluteolysin antibody; Trophoblast antiluteolytic protein antibody; Trophoblast protein 1 antibody; TP-1 antibody; Trophoblastin antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
- Host:
- Rabbit
- Immunogen:
- Recombinant Bovine Interferon tau-1 protein (24-195AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Bovine
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IFNT1-AntibodyFITC-conjugated-1091814.html
