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Antibodies

IL21R Antibody

Product Sizes
50 ul
£186.00
CSB-PA313276-50UL
100 ul
£334.00
CSB-PA313276-100UL
About this Product
SKU:
CSB-PA313276
Additional Names:
CD360 antibody; IL 21R antibody; IL-21 receptor antibody; IL-21R antibody; IL21 receptor antibody; IL21R antibody; IL21R_HUMAN antibody; Interleukin 21 receptor antibody; Interleukin-21 receptor antibody; MGC10967 antibody; NILR antibody; Novel interleukin receptor antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Host:
Rabbit
Immunogen:
Fusion protein of Human IL21R
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody